Week 1 |
|
| Buckeyes @ Boilermakers (-10) | |
| Bears @ Nittany Lions (-8) | |
| Jayhawks (-4) @ Wildcats | |
| Longhorns (-5) @ Tigers | |
| Bruins @ Crimson Tide (-3) | |
| Commodores @ Hawkeyes (-2) | |
| Yellow Jackets @ Cardinals (-5) | |
| Hokies @ Rebels (-1) | |
| Cyclones @ Bearcats (-5) | |
| Tar Heels @ Terrapins (-9) | |
| Blue Devils (-1) @ Tigers | |
| Badgers @ Golden Gophers (even) | |
| Sun Devils (-11) @ Cougars | |
| Mountaineers (-10) @ Razorbacks | |
| Wolfpack (-1) @ Fighting Irish | Game of the week |
| Orange (-3) @ Gamecocks | |
Week 3 |
|
| Yellow Jackets @ Blue Devils (-4) | |
| Tigers @ Hokies (-10) | |
| Crimson Tide @ Golden Gophers (-8) | |
| Razorbacks @ Bruins (-5) | |
| Tigers @ Bearcats (-4) | |
| Jayhawks @ Mountaineers (-4) | |
| Cyclones @ Cougars (-3) | |
| Bears @ Buckeyes (-5) | |
| Wolfpack @ Nittany Lions (even) | Game of the week |
| Boilermakers (-8) @ Gamecocks | |
| Badgers (-9) @ Hawkeyes | |
| Wildcats @ Sun Devils (-13) | |
| Cardinals @ Terrapins (-6) | |
| Rebels @ Longhorns (-10) | |
| Orange @ Fighting Irish (-3) | |
| Tar Heels @ Commodores (-2) | |
Week 4 |
|
| Hokies @ Blue Devils (even) | |
| Tigers @ Crimson Tide (-7) | |
| Golden Gophers (-2) @ Bruins | |
| Razorbacks @ Tigers (-5) | |
| Jayhawks (-6) @ Bearcats | |
| Cyclones @ Mountaineers (-15) | |
| Bears @ Cougars (-4) | |
| Wolfpack (-3) @ Buckeyes | |
| Boilermakers (-1) @ Nittany Lions | Game of the week |
| Gamecocks @ Badgers (-15) | |
| Hawkeyes @ Wildcats (-10) | |
| Terrapins @ Sun Devils (-12) | |
| Cardinals @ Longhorns (-10) | |
| Orange @ Rebels (-2) | |
| Fighting Irish (-2) @ Commodores | |
| Tar Heels @ Yellow Jackets (-4) | |
Week 6 |
|
| Fighting Irish @ Cardinals (-2) | |
| Golden Gophers @ Badgers (-6) | |
| Gamecocks @ Commodores (-4) | |
| Crimson Tide (-1) @ Tigers | |
| Boilermakers @ Terrapins (even) | Game of the week |
| Cougars @ Rebels (-5) | |
| Tigers @ Hokies (-6) | |
| Buckeyes @ Orange (-5) | |
| Bearcats @ Blue Devils (-2) | |
| Yellow Jackets @ Wolfpack (-10) | |
| Hawkeyes @ Cyclones (-6) | |
| Sun Devils (-12) @ Bears | |
| Bruins @ Jayhawks (-13) | |
| Longhorns (-7) @ Razorbacks | |
| Mountaineers (-10) @ Tar Heels | |
| Nittany Lions @ Wildcats (-3) | |
Week 9 |
|
| Tigers @ Hawkeyes (-3) | |
| Wolfpack (-4) @ Yellow Jackets | |
| Tar Heels @ Blue Devils (-5) | |
| Rebels @ Cyclones (-1) | |
| Longhorns (-3) @ Orange | |
| Commodores @ Gamecocks (-2) | |
| Bruins @ Wildcats (-6) | |
| Cardinals @ Hokies (-5) | |
| Tigers @ Razorbacks (-1) | |
| Mountaineers @ Badgers (even) | Game of the week |
| Bearcats @ Jayhawks (-12) | |
| Golden Gophers @ Sun Devils (-11) | |
| Nittany Lions (-1) @ Cougars | |
| Terrapins (-1) @ Buckeyes | |
| Crimson Tide @ Fighting Irish (-5) | |
| Boilermakers (-6) @ Bears | |
Week 10 |
|
| Cardinals (-1) @ Commodores | |
| Gamecocks @ Golden Gophers (-12) | |
| Bears @ Wildcats (-8) | |
| Terrapins @ Wolfpack (-5) | |
| Tar Heels @ Cyclones (-4) | |
| Yellow Jackets @ Nittany Lions (-7) | |
| Mountaineers (-7) @ Bearcats | |
| Fighting Irish @ Longhorns (-9) | |
| Badgers (-9) @ Tigers | |
| Hokies @ Crimson Tide (even) | Game of the week |
| Tigers @ Orange (-5) | |
| Razorbacks @ Rebels (-6) | |
| Blue Devils @ Jayhawks (-13) | |
| Buckeyes @ Cougars (-2) | |
| Boilermakers @ Sun Devils (-9) | |
| Bruins (-1) @ Hawkeyes | |
Week 11 |
|
| Badgers (-7) @ Bears | |
| Cyclones @ Tigers (-4) | |
| Bearcats @ Tar Heels (even) | |
| Boilermakers @ Wolfpack (-2) | |
| Terrapins (-2) @ Yellow Jackets | |
| Mountaineers (-8) @ Blue Devils | |
| Nittany Lions @ Buckeyes (even) | |
| Longhorns @ Sun Devils (-8) | |
| Rebels @ Jayhawks (-12) | |
| Hokies @ Fighting Irish (-2) | |
| Crimson Tide @ Commodores (even) | Game of the week |
| Wildcats @ Golden Gophers (-5) | |
| Bruins @ Cougars (-2) | |
| Hawkeyes @ Gamecocks (-3) | |
| Razorbacks @ Cardinals (-6) | |
| Tigers @ Orange (-9) | |
Week 12 |
|
| Crimson Tide @ Cardinals (-4) | |
| Badgers (-8) @ Commodores | |
| Hawkeyes @ Golden Gophers (-12) | |
| Tigers @ Bruins (-7) | |
| Hokies (-4) @ Gamecocks | |
| Wildcats (-1) @ Cougars | |
| Tigers @ Bears (-1) | |
| Orange (-1) @ Razorbacks | Game of the week |
| Rebels @ Fighting Irish (-4) | |
| Jayhawks @ Longhorns (-1) | |
| Nittany Lions @ Blue Devils (even) | |
| Yellow Jackets @ Mountaineers (-15) | |
| Bearcats @ Cyclones (-1) | |
| Tar Heels @ Wolfpack (-11) | |
| Terrapins @ Boilermakers (-6) | |
| Sun Devils (-10) @ Buckeyes | |
Week 13 |
|
| Commodores @ Crimson Tide (-6) | |
| Cougars @ Golden Gophers (-9) | |
| Sun Devils (-7) @ Wildcats | |
| Tigers @ Longhorns (-11) | |
| Mountaineers (-9) @ Cyclones | |
| Blue Devils @ Yellow Jackets (-2) | |
| Nittany Lions @ Terrapins (-4) | |
| Boilermakers (-4) @ Buckeyes | |
| Wolfpack (-2) @ Bearcats | |
| Tar Heels @ Jayhawks (-15) | |
| Rebels @ Razorbacks (even) | Game of the week |
| Cardinals (-2) @ Tigers | |
| Orange @ Hokies (-4) | |
| Gamecocks @ Fighting Irish (-9) | |
| Bears @ Hawkeyes (-1) | |
| Bruins @ Badgers (-11) | |
Week 16 |
|
| Mountaineers (-7) @ Rebels | |
| Tigers @ Commodores (-4) | |
| Orange @ Cardinals (-2) | |
| Bearcats @ Razorbacks (even) | Game of the week |
| Longhorns (-2) @ Hokies | |
| Gamecocks @ Crimson Tide (-7) | |
| Badgers (-5) @ Bruins | |
| Golden Gophers (-6) @ Hawkeyes | |
| Fighting Irish @ Tigers (-1) | |
| Bears @ Sun Devils (-18) | |
| Cougars @ Wildcats (-7) | |
| Yellow Jackets @ Buckeyes (-4) | |
| Terrapins @ Nittany Lions (-2) | |
| Wolfpack (-3) @ Blue Devils | |
| Cyclones @ Jayhawks (-14) | |
| Tar Heels @ Boilermakers (-12) | |